PANARTERITIS NODOSA PDF

Die Panarteriitis nodosa zeigt sich bei fast allen Betroffenen auch mit sehr unspezifischen Symptomen. Es wird jedoch davon ausgegangen, dass es sich um eine Autoimmunerkrankung handelt, die aufgrund vorheriger Infektionskrankheiten ausbricht. Die Symptomatik erinnert somit an eine Grippe. Es kommt zudem auch zu einer Blutunterversorgung der Nerven.

Author:Shakajora Dousar
Country:Laos
Language:English (Spanish)
Genre:Environment
Published (Last):14 October 2013
Pages:307
PDF File Size:6.4 Mb
ePub File Size:18.50 Mb
ISBN:712-4-22827-169-2
Downloads:31895
Price:Free* [*Free Regsitration Required]
Uploader:Malarn



Polyarteritis nodosa PAN is a rare disease that results from blood vessel inflammation " vasculitis " causing injury to organ systems. The areas most commonly affected by PAN include the nerves, intestinal tract, heart, and joints. PAN can also affect the blood vessels to the kidney resulting in high blood pressure and damage to kidney function. What is vasculitis? Vasculitis is a general term that refers to inflammation of the blood vessels. When inflamed, the blood vessel may become weakened and stretch in size, which can lead to aneurysms, or become so thin that they rupture resulting in bleeding into the tissue.

Vasculitis can also cause blood vessel narrowing to the point of closing off entirely so that organs become damaged from loss of oxygen and nutrients that were being supplied by the blood. PAN exclusively affects medium sized blood vessels. Who is affected by PAN? PAN can occur in people of all ages, from children to the elderly and appears to affect men and women equally. What causes polyarteritis nodosa PAN? The cause of PAN is unknown. PAN is not a form of cancer, it is not contagious, and it does not usually occur within families.

Evidence from research laboratories strongly supports that the immune system plays a critical role in PAN, causing blood vessel and tissue inflammation and damage. PAN is highly associated with hepatitis B infection. Since the hepatitis B vaccine was established, the rates of PAN have decreased significantly. What are the symptoms of polyarteritis nodosa PAN? Because many different organ systems may be involved, a wide range of symptoms are possible in PAN.

Patients who have PAN may feel generally ill and fatigued, have fevers, or have loss of appetite and weight. High blood pressure is common in PAN and usually due to vasculitis decreasing blood flow to the kidneys. PAN may affect nerves and cause abnormal sensations, numbness or loss of strength.

Any combination of these symptoms may be present.

LASERDRUCKER TESTDRUCK PDF

Polyarteritis nodosa

Polyarteritis nodosa PAN is a rare disease that results from blood vessel inflammation " vasculitis " causing injury to organ systems. The areas most commonly affected by PAN include the nerves, intestinal tract, heart, and joints. PAN can also affect the blood vessels to the kidney resulting in high blood pressure and damage to kidney function. What is vasculitis? Vasculitis is a general term that refers to inflammation of the blood vessels.

COURS DE PARASITOLOGIE MDICALE PDF

Panarteriitis nodosa: Entzündliche Gefäßerkrankung

Genetic diseases: PAN may be associated with inherited genetic forms of periodic fever syndromes, in particular a condition called Familial Mediterranean Fever FMF , which is especially common in patients from the Eastern Mediterranean. In this form, abdominal pains, muscle aches and bleeding around the kidney are common features. In this form joint pains and strokes are common. In all these genetic cases there may be a family history of similar problems, although not always in immediate family members parents, siblings, or grandparents , as the condition may be recessively inherited, so sometimes generations may be skipped. Who are affected?

BADBOY SEDUCTION PDF

Polyarteritis Nodosa

Central nervous system CNS lesions may occur 2 to 3 years after the onset of PAN and may lead to cognitive dysfunction, decreased alertness, seizures and neurologic deficits. Skin Skin abnormalities are very common in PAN and may include purpura, livedo reticularis, ulcers, nodules or gangrene. Skin involvement occurs most often on the legs and is very painful. Kidney Renal artery vasculitis may lead to protein in the urine, impaired kidney function, and hypertension. Small percentage of patients go on to require dialysis.

14081 DATASHEET PDF

Polyarteriitis nodosa

The cause remains unknown in the remaining cases; there may be causal and clinical distinctions between classic idiopathic PAN, the cutaneous forms of PAN, and PAN associated with chronic hepatitis. In polyarteritis nodosa, small aneurysms are strung like the beads of a rosary, therefore making "rosary sign" a diagnostic feature of the vasculitis. In polyarteritis nodosa, small aneurysms are strung like the beads of a rosary, [5] therefore making "rosary sign" an important diagnostic feature of the vasculitis. Nevertheless, their good discriminatory performances, indicated by the initial ACR analysis, suggested their potential usefulness for diagnostic purposes as well. Subsequent studies did not confirm their diagnostic utility, demonstrating a significant dependence of their discriminative abilities on the prevalence of the various vasculitides in the analyzed populations. When present, underlying hepatitis B virus infection should be immediately treated.

Related Articles